Metformine Hydrochloride

Generic name: Metformine Hydrochloride
Brand name: ……….
Pharmacotherapeutic group: Antihyperglycemic agent & Biguanide derivative
Therapeutic indication: Type 2 diabetes
Dosage and Administration: Tablet 500mg
Antihyperglycemic agent:
As monotherapy -Adult: oral; initially 500mg to 5mg two times a day, taken with morning and evening meals. The daily dose may be increased by 500mg at weekly intervals as needed.
Maintenance: oral, 500mg two to three times a day, taken with meals.
Pediatric: Safety and efficacy have not been established.
Side effect: Anemia, hypoglycemia, anorexia, diarrhea, dyspepsia, flatulence, headache, nausea or vomiting, metallic taste, weight loss
Information on the shelf life: 2 years

 
 

Glibenclamide

Generic name: Glibenclamide
Brand generic name: Minoo Glibenclamide ®
Pharmacotherapeutic group: Antidiabetic agent & sulfonylurea
Therapeutic indication: Type 2 diabetes
Dosage and Administration: Tablet 5mg
Adult: Initial; oral, 2.5 to 5mg once a day with breakfast or the first main meal, with dosage changes being made by no more than 2.5mg at weekly intervals if needed. Patients more sensitive to hypoglycemia may need 1.25mg a day.
Maintenance: oral, 1.25 to 20mg once a day of which doses up 10mg are usually taken as a single dose with breakfast or the first main meal, while doses over 10mg are usually divided into two daily doses with meals.
Pediatric: Safety and efficacy have not been established.
Side effect: Hypoglycemia, weight gain, erythema multiforme or exfoliative dermatitis, aplastic or hemolytic anemia, hepatic function impairment, eosinophilia, thrombocytopenia, changes in sense of taste, dizziness, drowsiness, gastrointestinal disturbances, headache, polyuria, blurred vision and photosensitivity
Information on the shelf life: 2 years